Focusing on internal functions, there are two categories that distinguish needleless connectors: simple and complex. Simple pinless connectors account for most of the pinless connectors.

The simple needle-free device contains no moving internal parts. On the other hand, complex connectors not only contain the movement of internal moving parts, but also depend on the movement of internal moving parts to enable the fluid to move successfully.

The movement of the fluid is to evaluate the characteristics of the needleless connector. Manufacturers often describe the motion of fluids as positive, negative, or neutral. Negative movement is where blood is drawn back into the catheter. Forward motion means holding a small amount of fluid and then pushing it into the catheter when disconnected. Neutral motion prevents fluid from moving into the catheter.

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