Cyclofenil powder (2624-43-3)
wisepoqder Cyclofenil powder (INN, USAN, BAN) (brand names Fertodur, Menopax, Ondonid, Ondogyne, Sexovid, others) is a selective estrogen receptor modulator (SERM) used as a gonadotropin stimulant which is or has been marketed in Europe, South Korea, Mexico, and Brazil, among other countries.
Cyclofenil
powder is a gonadal stimulant and inducer of ovulation. It is used in
the treatment of infertility and amenorrhea, but is thought to be less
effective than CLOMIPHENE.
05 Cyclofenil powder (2624-43-3) History
Cyclofenil powder (INN, USAN, BAN) (brand names Fertodur, Menopax, Ondonid, Ondogyne, Sexovid, others) is a selective estrogen receptor modulator (SERM) used as a gonadotropin stimulant which is or has been marketed in Europe, South Korea, Mexico, and Brazil, among other countries.
Cyclofenil was first introduced in 1970 under the brand name Ondogyne in France. Subsequently, it was introduced under the brand names Sexovid in Japan in 1972, Ondonvid in the United Kingdom in 1972, and Fertodur in West Germany in 1972 and Italy in 1974. It was also marketed as Sexovid in Sweden, Neoclym in Italy, and Klofenil in Turkey.
Cyclofenil was
studied in the 1970s as an agent to induce ovulation in infertile women.
It was then investigated as a possible treatment for scleroderma in the
1980s, but was found to be ineffective. Later study of its efficacy in
treating Raynaud’s phenomenon in people with scleroderma also found no
statistically significant benefit.
Cyclofenil powder is a
nonsteroidal antiestrogen that is used in the treatment of menstrual
disturbances and anovulatory infertility due to hypothalamic-pituitary
insufficiency
Cyclofenil is an analytical reference standard
categorized as an anti-estrogen. 1,2 Anti-estrogens, including
cyclofenil, have been used as performance-enhancing drugs in sports
doping. This product is intended for research and forensic applications
