Coluracetam (MKC-231) is a synthetic Racetam drug purported to be a
Nootropic compound. It does not have a large body of evidence
investigating it, but the mechanisms of action (as well as structute)
appear to be very distinct from other racetam compounds like Piracetam
or Aniracetam.Coluracetam Review
Coluracetam appears to interact with a process known as high affinity
choline uptake (HACU for short), which is the rate-limiting step of
drawing choline into a neuron for synthesis into the neurotransmitter
acetylcholine. Increasing the HACU rate appears to increase the activity
of cholinergic neurons, so it is a desired target for cognitive
enhancement.
Interventions in rats (as there is no human evidence currently) support
the usage of coluracetam at very low oral doses to preserve HACU that is
otherwise impaired by the use of research drugs that are known to
impair HACU. The limited evidence looking at the inherent effects of
coluracetam on the HACU of normal neurons has failed to find any
significant interaction.
Coluracetam has also been noted to associate with choline transporters
physically, but it is not known exactly what it does once associated.
Overall, there is currently insufficient evidence to support the usage
of coluracetam for cognitive enhancement. Further studies are needed to
see if it has a therapeutic role in instances where HACU may be impaired
(such as Alzheimer's disease).
Application:
Rat studies have shown that Coluracetam is helpful in reducing the
effects of learning deficits. Not only did it reduce these effects, but
it also did not have any of the normally expected side effects [4">.
This product is also considered to have great potential as a casual mood
enhancer and a powerful memory booster. There is even evidence to
suggest that the positive effects on the brain are semi-permanent
[5">.
Users also report a rather wide range of Coluracetam benefits. This
includes enhanced concentration and speed of cognition. Coluracetam also
helps with both short and medium term memory. There are also a number
of reports of being able to study and focus more easily while taking
this nootropic
Description:
Coluracetam also seems to have a bit of a stimulant effect. It should
help to shake off any of the morning dreariness if taken upon waking and
it may produce a nice, comfortable energy boost that can last well into
the day. A number of users have reported that this is able to help them
improve their motivation and ability to get things done. Another
interesting effect is the apparent enhancement of sounds and colors.
This can be compared to turning up the brightness on a TV or computer
screen, with sounds become fuller and richer
