Product name: Lorcaserin hydrochloride
CAS No.: 846589-98-8
Purity: 99.5%
M. F.: C11H14ClN· ClH
M. W.: 232.1525
Appearance: White or kind of white powder.
Use: Medicine reducing weight and antidepressants.
Description for the CAS 846589-98-8 Lorcaserin Hcl
Lorcaserin is a selective 5-HT2C receptor agonist, and in vitro testing
of the drug showed reasonable selectivity for 5-HT2C over other related
targets. 5-HT2C receptors are located almost exclusively in the brain,
and can be found in the choroid plexus, cortex, hippocampus, cerebellum,
amygdala, thalamus, and hypothalamus. The activation of 5-HT2C
receptors in the hypothalamus is supposed to activate
proopiomelanocortin (POMC) production and consequently promote weight
loss through satiety.
Lorcaserin Hydrochloride Appliation:Orlistat
1) Lorcaserin HCl is an FDA-approved prescription weight-loss medication
that, when used with diet and exercise, can help some overweight adults
with a weight-related medical problem, or obese adults, lose weight and
keep it off.
2) Lorcaserin hydrochlorideis a serotonin 2C receptor agonist. It
hasbeen shown to decrease food consumption and promote SA tiety by
selectivelyactivating serotonin 2C receptors in the brain.
3) Lorcaserin HCl is specifically indicated as an adjunct to a
reduced-calorie diet andincreased physical activity for chronic weight
management in clinically obeseadults (BMI of 30 kg/m2 or greater) and
overweight adults (BMI of 27 kg/m2 orgreater) with at least one
weight-related comorbid condition.
4) Lorcaserin HCl is supplied as a tablet designed for oral
administration. The recommendeddose is one 10mg tablet twice daily. Use
of Lorcaserin HCl should be discontinued if 5%weight loss is not
achieved by week 12 of treatment.
