Smart Nootropics 99% Dihexa Powder CAS 1401708-83-5 | Forum

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xysoom
xysoom Oct 7 '19

Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is anoligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.PNB-0408 powder

According to a patent, "Short duration safety studies with Dihexa have uncovered no apparent toxicity. Of particular note is a lack of neoplastic induction, since c-Met is recognized as an oncogene. This is unsurprising sinceoncogenesis requires multiple mutations including both oncogene induction and tumor suppressor attenuation."

Specification
Product Name: Dihexa
CAS No. : 1401708-83-5
Sequence: Hexanoyl-Tyr-Ile-Ahx-NH2
Molecular formula: C27H44N4O5
Molecular weight : 504.28
Purity: 98.0%min
Source: synthetic

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